Topical vs. Injectable PDGF+
Growth factors are shaping the future of skin and hair rejuvenation, and Platelet-Derived Growth Factor (PDGF+) is at the forefront of this change. Both topical and injectable PDGF+ share the same goal—stimulating repair, renewal, and collagen production—but the way they are delivered, and the results they provide, are different. Dr. JoAnna Nguyen helps patients choose the option that best matches their needs, comfort level, and long-term goals.
Understanding the Two Options
Topical PDGF+
Topical PDGF+ is applied directly to the skin, most often after microneedling. The microchannels created during treatment allow the growth factor serum to penetrate more effectively, signaling the skin to repair itself and produce collagen. This approach is completely non-invasive, requires no needles, and works beautifully for patients looking for subtle, natural improvements or ongoing maintenance.
Injectable PDGF+
Injectable PDGF+, on the other hand, is delivered through fine injections into the skin or scalp. By placing the growth factors deeper, this method directly activates fibroblasts, supports circulation, and can even awaken dormant hair follicles. Injectable PDGF+ is better suited for patients seeking more dramatic changes in skin firmness, elasticity, or hair growth. While minimally invasive, downtime is still very limited, with only mild redness or swelling at injection sites.
Click below to learn more about PDGF+ & other options for collagen stimulation!
Key Differences at a Glance
When comparing the two approaches, the differences are clear. Topical PDGF+ is non-invasive, enhances healing, and focuses on surface-level improvements, making it an excellent choice for patients wanting a gentle boost. Injectable PDGF+ requires needles but allows growth factors to work deeper in the skin, leading to more intensive repair and stronger results for those with advanced concerns.
Primary Purpose
Topical PDGF+
Overall skin healing and surface improvement
Injectable PDGF+
Targeted, specific rejuvenation for particular concerns
Delivery Method
Topical PDgf+
Non-invasive application to the skin’s surface
Injectable PDGF+
Directly delivered into the skin or the scalp with a needle
Comfort
Topical PDGF+
Minimal discomfort; numbing cream may be used with microneedling
Injectable PDGF+
Potential for discomfort and injection site reactions; numbing cream may be used
Downtime
Topical PDGF+
Typically less downtime, especially for post-procedure recovery
Injectable PDGF+
May have slightly more downtime, especially around sensitive areas like the eyes
Best For
Topical PDGF+
Enhancing results and speeding recovery after other cosmetic procedures
Injectabe PDGF+
Addressing specific issues like under-eyes bags, wrinkles, or hair loss
Choosing What’s Right for You!
Ultimately, the right option depends on your goals. If you want to enhance healing and see subtle improvements with no extra recovery, topical PDGF+ may be ideal. If your goals are more intensive—like addressing deeper wrinkles, skin laxity, or hair thinning—injectable PDGF+ can provide more powerful and lasting changes.
Both options are rooted in the same growth factor science and can be tailored to your unique needs.
Schedule a consultation with Dr. JoAnna Nguyen to discover whether topical or injectable PDGF+ is the best fit for your personalized treatment plan!